Knockout round second leg

Hamburg 3–1 Rapid Bucuresti

Scorers:
Hamburg: B Lauth 23, S Barbarez 35, R Van der Vaart 62

Rapid: M Buga 50

Aggregate: 3-3 (Rapid Bucuresti win on away goals)

Roma 2-1 Middlesbrough

Scorers:
Roma: A Mancini 42, 65 (pen)

Middlesbrough: J Hasselbaink 31

Sent off:
P Mexes 90

Aggregate: 2-2 (Middlesbrough win on away goals)

Sevilla 2–0 Lille

Scorers: F Kanoute 28, C Luis Fabiano 45

Sent off:
M Bodmer 25, JG Navas 70

Seville win 2-1 on aggregate

Thursday, 16 March 2006
Levski Sofia v Udinese (0-0)
Real Betis v Steaua Bucuresti (0-0)
Schalke 04 v Palermo (0-1)
Strasbourg v Basle (0-2)
Zenit St Petersburg v Marseille (1-0)